Chadwick Boseman died Friday at the age of 43, according to the Associated Press. The actor, best known for starring in Marvel’s Black Panther, was diagnosed with stage 3 colon cancer in 2016.

The Hollywood star died at home with his wife and family by his side. He had not spoken publicly about his diagnosis, which he had battled for four years.

Confirming the actor’s death, a statement posted to Boseman’s twitter said: “It is with immeasurable grief that we confirm the passing of Chadwick Boseman. Chadwick was diagnosed with stage III colon cancer in 2016, and battled with it these last 4 years as it progressed to stage IV.

“A true fighter, Chadwick persevered through it all, and brought you many of the films you have come to love so much. From Marshall to Da 5 Bloods, August Wilson’s Ma Rainey’s Black Bottom and several more, all were filmed during and between countless surgeries and chemotherapy. It was the honor of his career to bring King T’Challa to life in Black Panther.”

Boseman played black icons Jackie Robinson and James Brown early in his career before reaching megastardom playing Black Panther in the Marvel cinematic universe. The actor most recently starred in Spike Lee’s acclaimed Vietnam War drama Da 5 Bloods.

In a statement, Denzel Washington, a producer on the upcoming Ma Rainey’s Black Bottom, which will be Boseman’s final film, wrote: “He was a gentle soul and a brilliant artist, who will stay with us for eternity through his iconic performances over his short yet illustrious career. God bless Chadwick Boseman.”

His death stunned Hollywood and tributes have immediately begun pouring in from across the entertainment industry and beyond, including from fellow Marvel stars.