High-Fat Foods Might Affect Your CBD Absorption
According to the findings of a 2019 study, consuming high-fat foods might affect your cbd absorption process in the body.
When you take a pill orally, it must first make its way through your digestive system and be absorbed by the lining of your stomach or small intestine before it can enter your bloodstream and have the desired effect.
This process can take anywhere from one to three hours.
Because nutrients from the food that you consume get absorbed in a similar way, the food that you eat may affect how your body processes certain prescriptions - This is the reason why some drug labels urge patients to take the medication with or without meals or to avoid certain foods.
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Epidiolex (cannabidiol), a medication taken orally that contains CBD, a component of cannabis (marijuana) that does not cause intoxication, was granted approval by the FDA in 2018.
Although the medicine was found to be beneficial in trials conducted on people who suffered from severe epilepsy, it was not approved until after these studies were completed, and at the time, very little was known about how food would affect the drug.
However, due to the fact that CBD is a molecule that is soluble in fat, a number of specialists have hypothesized that one's diet could significantly affect the rate of absorption.
Evidence from the University of Minnesota about how high-fat foods might affect your CBD absorption reveals that the food you eat is an important factor to consider while taking CBD in the form of an oral supplement.
In the study, which was published in the journal Epilepsia, the researchers asked eight patients to take their CBD dose either on an empty stomach (after fasting overnight for at least 10 hours) or within 30 minutes of eating a high-fat breakfast burrito.
Both conditions were evaluated for their effects on patients with epileptic seizures.
Before the participants took their medication, their blood was checked, and then again a variety of times (ranging from 30 minutes to 72 hours) after they took it.
The findings of the study showed that individuals who had consumed a high-fat breakfast before taking their medication had blood levels of CBD that were at least four times higher (and up to 14 times higher) compared to the levels in individuals who had taken the medication after going without food for at least 12 hours prior to the study.
However, the findings of this study imply that taking an excessive amount of fat may also be hazardous.
Compounds that are fat-soluble, such as CBD, require that they be consumed alongside some fat in order to be adequately absorbed.
It is also important to note that any excess amount of fat-soluble chemicals that you consume gets stored in your body's fat reserves, so there might be a buildup over time.
This is something that should be taken into consideration.
Although this study was very brief, it explains,
The clinical importance of advising patients to take CBD consistently with food for uniform exposure, it might be useful to prescribe CBD twice a day to minimize fluctuations due to the difference when administered with meals of varying fat content.
Important - Because topical chemicals do not get digested through your digestive tract, it is possible that the food you consume will not have an effect on how well topical CBD works for you, for example, if you are using it to treat the pain of arthritis.
According to the study that was published in the journal Epilepsia, there were no differences in the patients' mental functioning regardless of whether or not they took CBD after eating or while fasting.
According to a statement made by study co-author Angela Birnbaum in a press release issued by the university,
The type of food can make a large difference in the amount of CBD that gets absorbed into the body. Although fatty foods can increase the absorption of CBD, it can also increase the variability, as not all meals contain the same amount of fat.
Ilo Leppik, who was involved in the study and indicated that greater CBD absorption can result in reduced pharmaceutical costs.
Professor positions are held by both Birnbaum and Leppik in the department of experimental and clinical pharmacology at the university.
According to Birnbaum,
For epilepsy patients, one of the goals is to maintain stable blood concentrations of medication. According to the findings of this study, the concentration of CBD in patients' systems might change greatly depending on how they take the medication, which may involve consuming it with or without meals. Variations in blood concentrations could make a patient more prone to seizures.
It has been discovered that eating fatty meals causes the body to manufacture "a natural feel-good chemical" known as endocannabinoids, which has effects that are comparable to those produced by marijuana.
At the very least, the "getting high" element of "smoking pot" will not cause you to gain weight.
When researchers learned that the body actually produces its own cannabinoids which are very small chemicals that alleviate both pain and anxiety, they made the discovery of endocannabinoids.
If it's any consolation, another way to stimulate your body's natural cannabinoids is to work out, which is not nearly as enjoyable as munching on Cheez Doodles.
A study found that excessive consumption of fatty meals caused effects that were comparable to those of cocaine addiction.
- Avocados (which promote the absorption of key nutrients like beta-carotene, alpha-carotene, and vitamin A as well!).
- Dark Chocolate.
- Fish high in omega-3 fatty acids, such as salmon, albacore tuna, and sardines.
- Nuts, particularly walnuts (exceptional source of omega-3 fatty acids), almonds, and pistachios.
Studies conducted on animals suggest that cannabidiol, or CBD, may also speed up the metabolism and decrease food intake by interacting with two receptors in the body known as CB1 and CB2, both of which are involved in the metabolic process.
Last but not least, CBD may encourage the browning of fat cells, the type of fat that is responsible for producing heat through the burning of calories.
The investigations revealed that CBD participates in various aspects of the body's dynamic relationship with fat.
According to the findings of the study, CBD aided in the transition of white fat cells into brown fat cells.
In addition to this, it encouraged the body to break down fat in a more effective manner.
No, you don't need fat for the absorption of CBD. CBD will absorb even if you don't take a high-fat diet. But, taking high-fat foods will increase the absorption of CBD in your body.
High-fat foods affect the absorption of CBD in your body as a study conducted in 2018 in the United States when CBD capsules were given to seizure patients.
A recent study suggests that taking the dosage of CBD supplements like CBD oil, CBD-infused products, etc. after a meal that is high in fat can boost the body's ability to absorb the compound by as much as 400 percent.
What is your take on how high-fat foods might affect your CBD absorption? Have you ever tried any CBD-infused products?
Have you heard about CBD drug interactions?